Updated June 2026
in a vacuum; used in the phrase in vacuo
“The experiment was conducted in vacuo to eliminate air resistance.”
"Vacuo" uses 5 different letters, which makes it efficient for eliminating options. Its 3 vowels help pin down vowel positions early.
"Vacuo" is worth 10 points before board bonuses. Aim its letters at double/triple-letter and word squares to lift the score.
Change a single letter of “vacuo” to make these 5-letter words — useful for Wordle and crossword clues.
Look up vacuo in an authoritative dictionary for full definitions, pronunciation, and etymology.

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