Loading word page…
Updated June 2026
A biological preparation that provides active acquired immunity to a particular infectious disease. Contains an agent resembling a disease-causing microorganism.
“The development of the polio vaccine was a major medical breakthrough.”
/vækˈsiːn/
vac·cine
Contains double C, INE ending, three vowels
Worth 14 points; valuable double C combination
Look up vaccine in an authoritative dictionary for full definitions, pronunciation, and etymology.
Download Word Challenge for unlimited word puzzles, a fresh Daily Challenge, and head-to-head multiplayer. Guess the hidden word in six tries or fewer!