Updated June 2026
plural of tophus; chalky deposits of uric acid in gout
“The tophi formed painful lumps on his joints.”
"Tophi" uses 5 different letters, which makes it efficient for eliminating options. Its 2 vowels balance the consonants.
"Tophi" is worth 10 points before board bonuses. Aim its letters at double/triple-letter and word squares to lift the score.
Change a single letter of “tophi” to make these 5-letter words — useful for Wordle and crossword clues.
Look up tophi in an authoritative dictionary for full definitions, pronunciation, and etymology.

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