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Updated June 2026
The refusal to accept or comply with something. The ability not to be affected by something, especially adversely.
“The bacteria developed resistance to antibiotics through prolonged exposure to the medication.”
/rɪˈzɪstəns/
re·sist·ance
Four 'E's and two 'S's; focus on vowel distribution
Worth 10 points; efficient for using common letters strategically
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