Histone
7 lettersnounrareUpdated June 2026
Definition
A basic protein found in cell nuclei that associates with DNA to form chromatin, helping to package and regulate genetic material.
“Modifications to the histone proteins can switch genes on or off without altering the DNA sequence.”
Pronunciation
Syllables
his·tone
Word Game Tips
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Wordle
Ends in -TONE, which looks like STONE with an H-I prefix. Contains three vowels: I, O, E.
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Scrabble
H scores 4, otherwise all common tiles. A biology term worth knowing for Scrabble, HISTONES adds an S hook.
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