Guanine
7 lettersnounmoderateUpdated June 2026
Definition
A purine nitrogenous base found in both DNA and RNA, which pairs with cytosine in the double helix.
“In the DNA molecule, guanine always bonds with cytosine via three hydrogen bonds.”
Pronunciation
Syllables
gua·nine
Related Words
Synonyms
g
Word Game Tips
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Wordle
Contains four vowels and ends in INE, and the GUA opening is uncommon making it a useful Wordle vowel guess
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Scrabble
GUANINE is vowel-heavy with four vowels and scores modestly, excellent for clearing surplus vowels from your rack
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